Can Losartan 50/12.5 hctz be cut in half?
Yes, losartan/HCTZ can safely be cut in half. In fact, many generic companies produce tablets with a "score" down the middle of the tablet to ease in cutting.
It's typically a good idea to always check to see whether or not your medication can be cut in half. Most extended release formulations should not be cut in half or altered. Doing so can ruin the extended release mechanism of the dosage form, potentially causing the entire dose to be released at once, which greatly increases the risk of side effects.
Fortunately, losartan/HCTZ is not extended release and can be safely cut.