Feb 22, 2019
louman19 asked
Can I cut a 1000mg Ranexa in half to get a 500mg dosage?
At a glance
- Ranexa tablets cannot be cut due to the extended-release mechanism. Cutting or splitting the tablets will release the entire dose at once, increasing the risk of side effects and shorten the duration of action of the drug.
Answer
Ranexa (ranolazine) tablets should not be cut or split in half, unfortunately. Additionally, they should not be crushed or chewed. The tablets are only intended to be swallowed whole.
The prescribing information for Ranexa states the following regarding instructions for administration:
References
- Elsevier ClinicalKey: Ranexa Monograph (Accessed 2/22/19)
- Ranexa Prescribing Information
- Clinical Pharmacokinetics of Ranolazine. Springer Link
