Can I take cheratussin with Sinex night time? I’m 6’2” and 250 lbs and I’m having trouble sleeping because of sinus pressure and cough/chest congestion.
Sinex comes in multiple formulations (as discussed below). Most are safe to take with Cheratussin (guaifenesin/codeine) but you do want to avoid nighttime Sinex formulations due to the risk of additive sedative effects from both. Below are the common Sinex formulations along with a note regarding whether or not they are safe to take with Cheratussin.
Sinex Daytime Liquicaps
Sinex Daytime is safe to take with Cheratussin and there is no interaction between the two.
Sinex Nighttime Liquicaps
Sinex Nighttime should not be taken with Cheratussin. Sinex Nighttime contains doxylamine, a sedating second generation antihistamine. Combining both could cause excess sedation and increase the risk of side effects such as confusion, dry mouth, dry eyes and constipation.
Sinex Nasal Spray
Cheratussin is safe to take with most Sinex products. It should not however be taken with Sinex Nighttime.