Taking Amoxicillin With Tylenol Cold & Sinus

In our latest question and answer, the pharmacist discusses whether or not there is an interaction between amoxicillin and Tylenol Cold and Sinus.

Jul 18, 2018

Lily asked

Hello, I have been taking amoxicillin since Sunday for a throat infection. Today, I started developing cold symptoms. Is it safe to take Tylenol Cold and Sinus in conjunction?

Answer

Tylenol Cold & Sinus (acetaminophen; pseudoephedrine) is safe to take with amoxicillin. There is no drug interaction between the two.

A comparable product in the United States is Tylenol Sinus & Headache (acetaminophen; phenylephrine). That is also safe to take with amoxicillin as there are no known drug interactions between the two.

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