Is There An Interaction Between Alcohol And Eliquis?

In our latest question and answer, the pharmacist discusses whether or not there is an interaction between alcohol and the blood thinner Eliquis.

Is There An Interaction Between Alcohol And Eliquis?
May 31, 2020

Jerry asked

I am wondering if it is safe to drink alcohol if I am taking Eliquis?

At a glance

  • Product labeling for Eliquis doesn't list an interaction with alcohol.
  • Since Eliquis is metabolized in the liver, alcohol-induced liver disease could negatively influence the effects of the drug.
  • Excessive alcohol consumption can increase the risk of certain bleeding events, like gastrointestinal bleeds.
  • Be sure to talk with your doctor about whether or not alcohol is safe to consume with Eliquis for your specific medical situation.

Answer

The prescribing information for Eliquis (apixaban) doesn't list alcohol as potential drug interaction and when consumed responsibly, is thought to be relatively safe (especially when compared to other blood thinners, like warfarin).

Having said this, two things need to be noted:

  • Eliquis is metabolized by the liver and those with moderate to severe liver impairment with likely see a change in how effective the drug is. Heavy alcohol consumption, as we well know, can cause liver damage.
  • Long-term alcohol consumption can increase the risk of certain types of bleeding, like upper gastrointestinal bleeds. Combined with a blood thinner, this risk could be further increased.

Overall, if you are in good health and don't over-consume alcohol, Eliquis is generally considered to be safe when combined with it.

'Safe' levels of consumption, for most individuals, is generally considered to be no more than one to two servings per day.

A serving is equal to:

  • Beer (12 ounces)
  • Wine (5 ounces)
  • Liquor (1.5 ounces)

Since everyone's medical situation is unique, it is best to discuss this with your doctor for advice that is appropriate to your situation.

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