Jul 31, 2018
Brian asked
How long does amoxicillin stay in your system?
Answer
We have written a few articles on this subject, which can be found here:
Below are some highlights from that article:
- Amoxicillin has a short half-life relative to other drugs, around 1 to 1.5 hours. 'Half-life' refers to the time it takes our bodies to metabolize 50% of a drug.
- Most of your amoxicillin dose will be eliminated within 12 hours (this is why it needs to be dosed 2-3 times daily). More than 60% will be eliminated via the urine 6 hours after your last dose.
- Elimination time can be prolonged in patients with kidney disease. There are reports that the half-life of amoxicillin is extended to over 12 hours in those with end-stage kidney disease.
- Amoxicillin will last longer in pediatric patients less than 12 weeks of age due to incompletely developed renal function.
