Does Butrans Contain Sulfa?

In our latest question and answer, the pharmacist discusses whether or not the Butrans patch has sulfa containing components.

Does Butrans Contain Sulfa?
Jan 07, 2018

JoAnn asked

Does Butrans patches contain sulfa?


No, Butrans (buprenorphine) patches do not have 'sulfa' containing components and may be safely used in those with 'sulfa' allergies.

Butrans Ingredients

Butrans contains the following ingredients:

  • Buprenorphine
  • Levulinic acid
  • Oleyl oleate
  • Povidone
  • Polyacrylate cross-linked with aluminum

Below, is the chemical structure of buprenorphine:

Buprenorphine Chemical Structure

As you can see, there are no sulfa structures contained in buprenorphine. It is considered safe to use in those with known allergies or sensitivities to sulfa containing drugs.

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