When Is The Best Time To Get The Second Shingrix Shot?

In our latest question and answer, the pharmacist discusses the best time to get your second shot of Shingrix.

Jul 10, 2018

Shirley asked

After your first Shingrix shot I understand that the second dose should be 2-6 later. My question is, in order to be the most effective what month after the first shot was given is the most effective. In other words, is exactly 2 months after too soon? Would waiting for month 3 or 4 be better?


The dosing recommendation for Shingrix is as follows:

  • Healthy adults 50 years and older should get two doses of Shingrix, 2 to 6 months apart.

In regard to the second dose, there is no "ideal" month during the two to six month time frame. According to the prescribing information for Shingrix, there is no significant difference in efficacy or adverse effects, regardless of the month the second dose is given (as long as it is 2 to 6 months after the first dose):

"The safety profile of SHINGRIX was similar when administered according to a 0- and 2-month or 0- and 6-month schedule."

You can feel comfortable getting your second dose anytime during the 2-6 month window.

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