Eliza asked
Im 13 weeks pregnant and took 2 Aleve liquid gels without even thinking about it. I know it's a no-no during pregnancy so I'm wondering if taking it one time will hurt the baby?
Answer
When it comes to safe pain relievers to use during pregnancy, Tylenol (acetaminophen) is the recommended product according to multiple guidelines.
In most situations, the use of NSAIDs (Non-steroidal anti-inflammatory) should be avoided. Over the counter NSAIDs include:
- Advil (Ibuprofen)
- Motrin (Ibuprofen)
- Aleve (Naproxen)
Aleve (Naproxen) Use During Pregnancy
As stated above, NSAIDs, such as Aleve (naproxen) should be avoided during pregnancy.
Using NSAIDs, such as Aleve, during the first 20 weeks of pregnancy has been associated with an increased risk of miscarriage, but this isn't conclusive. Nevertheless, the FDA did release a safety announcement in regard to this.
In addition, there is a minor association between using NSAIDs in the first trimester and the following birth defects:
- Small or absent eyes
- Neural tube defects
- Oral clefts
- Amniotic band syndrome
- Pulmonary valve stenosis
The above side effects are according to this study, which concluded:
"The use of NSAIDs [e.g. Aleve] in early pregnancy does not appear to be a major risk factor for birth defects, although there were a few moderate associations between NSAIDs and specific birth defects."
What is more conclusive regarding NSAID use is that they should absolutely be avoided during the 3rd trimester due to the risk of
- Closure of ductus arteriosus
- Fetal renal toxicity
- Bleeding
It is difficult to determine the risk of side effects from one time dosing of Aleve during the first trimester. Some studies indicate short term use is relatively safe, as long as it isn't during the last trimester of pregnancy and Tylenol (acetaminophen) isn't an option.
Be sure to speak with your doctor regarding the best analgesic options for use during pregnancy in your particular situation.
