Is Zolpidem The Same As Zolpidem Tartrate?

In our latest question and answer, the pharmacist discusses whether or not there is a difference between zolpidem tartrate.

Jul 09, 2018

Kristen1 asked

My new doctor rx'd me Ambien 10mg (1 tablet per night for insomnia). Everytime I get it filled, it just says zolpidem, as opposed to zolpidem tartrate, which I think is what I used to get. Its made by Teva, but I feel like it's not as strong as the tartrate one. Is the zolpidem that I'm getting now the same thing as the zolpidem tartrate 10mg?

Answer

All Ambien products contain the active ingredient zolpidem tartrate.

There are no less than 7 different generic manufacturers of zolpidem tartrate, including Teva, Actavis, Northstar and Apotex. The fact that your pharmacy sometimes labels your prescription as "zolpidem" and sometimes as "zolpidem tartrate" is most likely just how they have their drug files set-up in their pharmacy software. Rest assured that all zolpidem products are zolpidem tartrate.

In regard to you feeling different effects with different manufacturers, this isn't overly common but it isn't unheard of. Although every generic Ambien product contains the same active ingredient and has been deemed substitutable and bio-equivalent per FDA standards, different products do contain different inactive ingredients, which may cause a slightly difference in how a particular medication is tolerated.

For example, one manufacturer may add lactose to their tablets, which can certainly cause tolerability issues for some patients. Often times, you can request your pharmacy to fill the same generic manufacturer every time for you, assuming that it is available to them.

To illustrate the difference between two zolpidem products, below are the ingredients lists for two different manufacturers of zolpidem tartrate 5 mg.

Northstar Zolpidem 5mg Tablet:

  • Zolpidem Tartrate 5 mg
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Microcrystalline Cellulose
  • Polyethylene Glycol
  • Sodium Starch Glycolate
  • Titanium Dioxide

Mylan Zolpidem Tartrate 5mg Tablet:

  • Zolpidem Tartrate 5 mg
  • Calcium Phosphate Dibasic
  • Crospovidone
  • D&C Red No. 30
  • FD&C Blue No. 2
  • FD&C Yellow No. 6
  • Hypromellose
  • Lactose
  • Magnesium Stearate
  • Microcrystalline Cellulose
  • Polydextrose
  • Polyethylene Glycol
  • Povidone
  • Sodium Lauryl Sulfate
  • Titanium Dioxide
  • Triacetin

Contents

Ready for a more personal experience with your meds?