Drug Interaction: Bupropion And Sudafed PE

The pharmacist discusses whether or not there is an interaction between bupropion and Sudafed PE (phenylephrine).

Jul 01, 2018

Patty asked

Can I take Sudafed PE with bupropion hcl xl 300 mg?

Answer

There are no known drug interactions between Sudafed PE (phenylephrine) and bupropion XL. They are considered safe to take together.

It is always a good idea to look into potential drug interactions when you are taking prescription medication, especially with antidepressants like bupropion as they can be involved in some dangerous ones. However, phenylephrine is not known to interact with bupropion, and they do not share similar side effects.

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