Terri asked
My 9 year old granddaughter has been on ADHD meds since she was 5 yrs old. They are: Adderall and clonodine. She has had pimples and a horrible under arm odor (like onions) since she has taken these meds. Her doctor is not concerned but we are! Are these drugs known to cause these symptoms? Where should we turn? Thank you for your help.
Answer
An increase in body odor or acne are not reported or listed side effects of clonidine or Adderall. However, both medications are known to increase diaphoresis (i.e. sweating). An increase in sweat can easily contribute to stronger than usual body odor, and depending on how often or well you cleanse your face, could certainly increase facial acne.
The prescribing information for Adderall lists that around 2-4% of individuals taking the drug will experience an increase in sweating. The prescribing information for Clonidine states that around 5% of individuals taking the medication will have an increase in sweating. Taking both drugs together can certainly increase the risk of this side effect.
In addition, both Adderall and clonidine have complex mechanisms of action, and affect many different parts of the body. Adderall specifically increases the release of numerous neurotransmitters such as dopamine, norepinephrine and serotonin. Increases in these neurotransmitters could certainly affect other parts of the body.
Lastly, according to the FDA Adverse Events Reporting System, there have been anecdotal reports of an increase in body odor and acne with both clonidine and Adderall.
There may be options to switch medication or change dosage if these side effects are bothersome. In addition, it is important that proper hygiene be followed (e.g. washing face twice daily, using deodorant/anti-antiperspirant). Be sure to speak with the doctor regarding the options available to you.
