Can You Take Mucinex And DayQuil Together?

In our latest question and answer, the pharmacist discusses whether or not Mucinex (guaifenesin) can be taken with DayQuil.

Jan 23, 2018

Ashley asked

Also, can you take Mucinex and Dayquil together?

Answer

Mucinex can safely be taken with DayQuil as there is no interaction between the medications. However, DayQuil comes in a variety of additional brand formulations, some of which contain the active ingredient in Mucinex (guaifenesin). It is not be recommended to take Mucinex with any DayQuil product that contains guaifenesin. It is important to carefully review each products ingredients to avoid taking too much of the same drug.

See below for a breakdown of the ingredients in some of the Dayquil products.

Which DayQuil Products Contain Mucinex (Guaifenesin)?

Dayquil Cold & Flu

  • Acetaminophen (analgesic)
  • Dextromethorphan (cough suppressant)
  • Phenylephrine (nasal decongestant)

Dayquil Severe Cold & Flu

  • Acetaminophen (analgesic)
  • Dextromethorphan (cough suppressant)
  • Phenylephrine (nasal decongestant)
  • Guaifenesin (expectorant)

Dayquil Cough Suppressant

  • Dextromethorphan (cough suppressant)

Dayquil Cough & Congestion

  • Dextromethorphan (cough suppressant)
  • Guaifenesin (expectorant)
Summary

To reiterate, it is safe to take Mucinex (guaifenesin) with the original DayQuil (Cold & Flu) formula as that product does not contain guaifenesin. However, Mucinex should not be used with any DayQuil product that contains guaifenesin already (such as DayQuil Cold & Flu Severe). Be sure to carefully read the product packaging to avoid taking duplicate or unnecessary medications. Try and match your symptoms to the particular ingredients that you need when possible! 

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