Audra asked
Can I take a 5 mg of hydrocodone/acetaminophen (Norco) if I took 25mg of Benadryl 9 hours ago?
Answer
Benadryl (diphenhydramine) and Norco should be used at the same time with caution as the potential for additive sedative effects could be dangerous. However, it is considered safe to take hydrocodone (which is contained in Norco) about 6 hours after taking Benadryl as the effects will have worn off by that time.Benadryl reaches its peak sedative effect one to three hours after a dose is taken and its therapeutic effects generally last for four to six hours. It should be noted that it does take about one to two days for Benadryl to be completely cleared from your system, so there is still a risk (albeit small) of additive side effects until after 1-2 days.
Hydrocodone/Acetaminophen
Norco, which contains hydrocodone and acetaminophen, is a opiate agonist that is indicated for the treatment of moderate to severe pain. Hydrocodone may be given with food or milk to help prevent GI irritation. You should titrate the dose of hydrocodone slowly, utilizing the lowest effective dose to minimize the possibility of side effects. Common side effects associated with taking hydrocodone include but are not limited to:
- Constipation
- Drowsiness
- Nausea
- Euphoria
Benadryl (Diphenhydramine)
Benadryl (diphenhydramine) is a sedating antihistamine used most commonly for the treatment of allergic reactions, seasonal allergies, symptoms associated with the common cold and insomnia. Benadryl may be taken without regard to meals. commonly reported side effects associated with taking Benadryl include but are not limited to:
- Drowsiness
- Dizziness
- Fatigue
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Dry mouth
