Can Nortriptyline Capsules Be Opened?

In our latest question and answer, the pharmacist discusses whether or not nortriptyline capsules can be opened and sprinkled onto food.

Jul 15, 2018

pr98382 asked

Can nortriptyline capsules be opened and sprinkled on food? These are not extended release.


Yes, nortriptyline capsules can safely be opened and sprinkled onto food to ease administration.

In general, it is recommended to sprinkle the contents of a capsule onto an easy to consume food, to ensure complete ingestion of the entire dose. Such foods include apple sauce, pudding or yogurt. 

Lastly, it is important to note that it is not thought that food affects the rate or extent of nortriptyline absorption in a significant manner, so you can feel comfortable opening the capsules and sprinkling the contents on food if that is the easiest way to take a dose for you.

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