Can Diet Pills Cause A False-Positive Opioid Test?

In out latest question and answer, the pharmacist discusses whether or not diet pills can cause a false-positive drug test for opioids or narcotics.

Can Diet Pills Cause A False-Positive Opioid Test?
Jul 26, 2018

Lizzie asked

I'm just wondering if I'm being tested for narcotics, will taking a diet pill or pills such as truFix and truVision cause any kind of problems such as a false positive? I would just like to be sure that nothing along those lines will happen before I start taking diet pills.

At a glance

  • No specific diet pill product (with the possible exception of kratom) is known to cause false-positives for opioids on drug tests.
  • Nevertheless, there are countless reports of supplements containing adulterated or misbranded ingredients, which could theoretically cause you to fail a drug test.

Answer

Diet Pills With Tape Measure Around Them Stock Image

There have been very few studies looking at whether or not any dietary supplements can cause a false-positive test for narcotics, like opioids.

However, false-positives with urine-based drug tests are fairly common, so it stands to reason that some supplements may cause a false positive, especially if they are tainted with unmarked/unlabeled substances.

In addition, there are many documented drugs that are known to cause false positives for opioids.

We have written extensively on the subject of false-positives for drug tests, which can be found here: What Causes False-Positives On Urine Drug Tests? Below are some highlights from that article:

References
  1. Tainted Products Marketed as Dietary Supplements. AccessFDA
  2. Commonly prescribed medications and potential false-positive urine drug screens. PubMed
  3. Urine drug screening: practical guide for clinicians. PubMed

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