What is the difference between Benadryl and ZzzQuil? I want something for sleep.
Both Benadryl and ZzzQuil have the same active ingredient, diphenhydramine, and thus have nearly identical effects.
The differences between the two products lie in the inactive ingredients and dosage forms available.
Both Benadryl and ZzzQuil are available in multiple dosage forms, including:
Both Benadryl and ZzzQuil contain 25 mg of diphenhydramine per Liquicap.
ZzzQuil also has a product that contains melatonin, instead of diphenhydramine, and is called ZzzQuil Pure Zzzs.
Lastly, Benadryl is available in additional dosage forms that ZzzQuil is not available in, including:
When it comes to the liquid forms of the drugs, ZzzQuil contains alcohol (10% by volume) while the Benadryl liquid does not contain any alcohol. In fact, Benadryl as a liquid only comes as a "children's liquid", which is still the same active ingredient (diphenhydramine), just alcohol free.
The concentration of the ZzzQuil liquid is:
The concentration of Children's Benadryl liquid is:
The complete ZzzQuil liquid inactive ingredient list is as follows:
The complete Benadryl Children's liquid inactive ingredient list is as follows:
Besides the addition of alcohol to ZzzQuil liquid, it also contains high fructose corn syrup. Children's Benadryl liquid does not contain high fructose corn syrup, but sucrose instead.